The Mysterious Mysteries of Mystery Manor is an American animated mystery-supernatural-comedy television series, being created by Man of Action. It is produced by Man of Action Studios and Cartoon Network Studios and it airs on Cartoon Network since October 13th, 2015.
A brother and sister along with their sarcastic talking cat move into a mysterious mansion filled with supernatural beings and new friends.
- Frank Woodson (voiced by Greg Cipes) - a 15-year-old shy teenager who discovers the mysteries of Mystery Manor.
- Emma Woodson (voiced by Ashley Johnson) - Frank's 18-year-old sister who is intelligent and cares for animals.
- Tyler the Cat (voiced by Charlie Adler) - a sarcastic talking cat who is Emma's pet.
- Professor Woodson (voiced by Liam O'Brien) - a mysterious man who is Tyler and Emma's uncle.
- Tiffany (voiced by Kath Soucie) - the maid in Mystery Manor who is way more action-packed than what she lets on.
- The Friendly Banshee (voiced by Rob Paulsen) - a friendly banshee who lives in Woodson's refrigerator.
- Alexis "Alex" LeStorm (voiced by Elizabeth Daily) - a bully who likes to torment Frank and Emma.
- Julia Juneson (voiced by Grey Griffin) - a nerdish girl who gains a crush on Frank.
- Theodore "Teddy" Blake (voiced by Will Friedle) - a cool teenager who loves being cool.
- Harry the Gnome (voiced by Jim Cummings) - a magical gnome who lives in the Manor's gardens.
- Bella the Light Witch (voiced by Kristin Chenoweth) - an ancient witch who believes in hope and peace.
- Ghosty (voiced by Jeff Bennett) - a prankster ghost.
- Mayor Vanessa McCreep (voiced by Cristina Pucelli) - the mayor of Lightburrow.
- Dr. Mad Stitches (voiced by Keith David) - a mad scientist who seemly lives in the basement of the Mystery Manor.
- Madame Banshee (voiced by Jennifer Hale) - a banshee who hates mankind.
- The Black Queen (voiced by Andrea Baker) - a young, wicked and immortal queen.
- The Black Knight (voiced by Greg Baldwin) - an immortal knight who serves the Black Queen.
- The Dragon (voiced by Khary Payton) - a vile and dangerous red dragon.
- Rodagog (voiced by Mark Hamill) - a orc who loves treasure.
- Maria the Dark Witch (voiced by Kaley Cuoco) - Bella's cruel sister who believes in the exact opposite taking pleasure in chaos and hate.
- Mr. Conny (voiced by Eric Bauza) - a mysterious con-man who sells fake items.
- The Chimera (vocal effects by Frank Welker) - a creature with numerous body parts.