Justin and Burgess are called by Agent Welles that they must protect the crown of anubis.
- Justin Blake (Ben Stiller)
- Lt. Burgess Banks (Chris Rock)
- Agent Vincent Welles (Clark Gregg)
- Otis Preston (Alfred Molina) - the head of Cincinatti Mine Qaurters
- Anastasia Jett (Christine Taylor) - Justin's girlfriend and later wife
- Pierce Kirkland (Jon Bernthal) - former criminal turned agent of Cincinatti Mine Quarters, still holds a grudge against Burgess, with Burgess holding the same grudge against him
- Proctor Johnson (Udo Kier) - Roy Clay's scientist!
- Johan Clements (Geoffery Rush)
- Ferris Blake (Patrick Dempsey) - Justin's older Brother
- Sensei Woo (George Takai)
- Brianna Flint (Ann Hatheway)
- Captain Morris Johnson (George Lopez) - Burgess's new boss!
- Roy Clay (Tony Todd) - the main antagonist, and wants the Crown to bring an army of Jackal men!
- Police Officer (Andre Braugher)
- Lifegaurd (Jessica Alba)
- Librarian (Robin Atkin Downes)
Egypt: Cairo 2:00 P.M.
a mysterious figure sneaks into the Sphinx to steal the Crown of Anubis, but was foiled to realize it was a fake the whole time!